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Blood samples were collected from the men to determine their free and total testosterone levels. Total testosterone is the amount of both bound (and biologically inactive) and unbound testosterone. Free testosterone is the amount of the hormone present in the bloodstream that is not bound to protein. However, even with the nine rigorously selected symptoms, differences in testosterone levels between symptomatic and non-symptomatic men were marginal, highlighting the weak overall association between symptoms and testosterone levels. The link between the decline in testosterone levels seen in older men and late-onset hypogonadism (also known as male menopause) has long been a subject of debate. The concept of the Andropause (Male Menopause) is still considered controversial, but the latest research has finally officially identified the symptoms associated with a reduction in testosterone in older men. 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